Titanium dioxide (TiO 2) is a nontoxic white pigment for use in the manufacture of paints, plastics, paper, ink, rubber, textile, cosmetics, leather, and ceramics, and as adjuvant and additives in commercial formulations also TiO 2 is considered to be nontoxic and harmless, that is approved for use in food up to 1% weight in the final product, additionally are …